Abstract
Predictive genetic testing for Huntington's disease (HD) and hereditary breast and ovarian cancer (HBOC) is a relatively new medical test. Research to date, has focused on: (1) the psychological impact of genetic testing, (2) disclosing of results, (3) the impact of genetic testing on HD families, and (4) individual's assessment of risk. The purpose of this study was to examine how individuals experience predictive genetic testing for HD and HBOC and what impact that experience has on individuals and family members. A grounded theory study design employing in-depth interviewing, theoretical sampling, and dimensional analysis was performed. Interviews with 29 participants were completed: 17 HBOC participants and 12 HD participants. The sample included individuals who tested: (1) negative for HD, (2) positive for HD, (3) positive for BRCA1/BRCA2 and (4) one participant from each group who decided against testing. Analysis revealed that individuals and their families are changed by predictive genetic testing.
Sigma Membership
Delta Phi
Type
Dissertation
Format Type
Text-based Document
Study Design/Type
Grounded Theory
Research Approach
Qualitative Research
Keywords:
Hereditary Cancers, Predictive Genetic Testing, Huntington's Disease
Advisor
Barbara Bowers
Second Advisor
Nadine Marks
Degree
PhD
Degree Grantor
University of Wisconsin-Madison
Degree Year
2003
Recommended Citation
Hamilton, Rebekah J., "Experiencing predictive genetic testing in families with Huntington's disease and hereditary breast and ovarian cancer" (2022). Dissertations. 287.
https://www.sigmarepository.org/dissertations/287
Rights Holder
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All permission requests should be directed accordingly and not to the Sigma Repository.
All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
Review Type
None: Degree-based Submission
Acquisition
Proxy-submission
Date of Issue
2022-08-04
Full Text of Presentation
wf_yes
Description
This dissertation has also been disseminated through the ProQuest Dissertations and Theses database. Dissertation/thesis number: 3101451; ProQuest document ID: 305285011. The author still retains copyright.