Abstract

Acidemia is common in cardiac patients undergoing coronary artery bypass graft (CABG) surgery. Acute metabolic acidosis (MA) during CABG surgery is typically an indication of tissue hypoperfusion.1,2,3,4 This pH imbalance is thought to contribute to cardiac instability, reduced responsiveness to vasopressors, and increased mortality.1,2,5 As a result, anesthesia providers commonly administer sodium bicarbonate (SB) in efforts to correct the pH imbalance and restore cardiac function.1 Despite its prevalence, little evidence supports treating hypoperfusion-related MA with SB. This leads to the question, in patients undergoing CABG who develop MA intraoperatively, does correcting the pH with SB reduce postoperative mortality?

Author Details

Madeline DeBuys, BSN, RN and David Fort, DNP, CRNA

Sigma Membership

Non-member

Type

DNP Capstone Project

Format Type

Text-based Document

Study Design/Type

Case Study/Series

Research Approach

Translational Research/Evidence-based Practice

Keywords:

Sodium Bicarbonate, Coronary Artery Bypass Grafting, Lactic Acidosis

Advisor

David Fort

Second Advisor

Lisa Herbinger

Degree

DNP

Degree Grantor

Samford University

Degree Year

2025

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record. All permission requests should be directed accordingly and not to the Sigma Repository. All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

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Proxy-submission

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Abstract.pdf (142 kB)

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