Abstract

Background: Obesity is a major driver of healthcare spending in the United States. GLP-1 receptor agonists are effective for weight management; however, high rates of early discontinuation reduce both clinical and economic value.

Methods: A pre–post quality improvement project implemented a nurse-led follow-up call at four weeks.

Results: Adherence improved significantly (p=0.009), weight decreased by 10 pounds (p=0.023), and estimated annual savings per patient were $6,472, contingent on sustained long-term adherence. Total estimated project savings were $80,141.

Conclusion: Nurse-led follow-up calls are a high-value intervention supporting economic sustainability.

Author Details

Hanna Weitzman-Flanigan DNP, MSN, ANP-C, RN, CNOR, CNOR-GEN 29 years experience Expertise in Surgery/ Per-Operative/ Surgical Quality

Sigma Membership

Upsilon Chi

Type

DNP Capstone Project

Format Type

Text-based Document

Study Design/Type

Quality Improvement

Research Approach

Translational Research/Evidence-based Practice

Keywords:

Obesity, Obesity Medication Adherence, Evidence-Based Practice, Endocrinology, Metabolism, Glucagon-like Peptide-1 Agonists, Patient Compliance

Advisor

Virginia L. Waters

Second Advisor

Kathleen Brown

Third Advisor

Kimberly Sand

Degree

DNP

Degree Grantor

Nova Southeastern University

Degree Year

2026

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record. All permission requests should be directed accordingly and not to the Sigma Repository. All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Self-submission

Date of Issue

2026-07-07

Full Text of Presentation

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