Abstract
This study aimed to evaluate the feasibility, tolerability, acceptability, and preliminary effectiveness of cold therapy for managing vincristine-induced peripheral neuropathy in children with cancer. Specifically, the project tested whether nurse-led cold therapy using cooling gloves and socks during vincristine administration could reduce neuropathy symptoms and pain while improving quality of life. The study also sought to generate preliminary pediatric evidence to support future larger randomized controlled trials and inform the integration of safe, non-pharmacological symptom management strategies into pediatric oncology nursing care.
Sigma Membership
Non-member
Type
Report
Format Type
Text-based Document
Study Design/Type
Randomized Controlled Trial
Research Approach
Pilot/Exploratory Study
Keywords:
Pediatric Oncology, Vincristine, Peripheral Neuropathy, Cold Therapy
Recommended Citation
Şahin, Remziye Semerci, "The Effect of Cold Therapy on the Level of Vincristine-Induced Peripheral Neuropathy: A Pilot Randomized Controlled Trial" (2026). Sigma Foundation for Nursing Research Grant Reports. 204.
https://www.sigmarepository.org/grant_reports/204
Rights Holder
All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record. All permission requests should be directed accordingly and not to the Sigma Repository. All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
Review Type
None: Sigma Grant Recipient Report
Acquisition
Proxy-submission
Date of Issue
2026-05-07
Full Text of Presentation
wf_yes
Funder
Sigma Foundation for Nursing
Description
The author has published an article on this grant-funded topic. The article is not posted in this repository; the citation is for information purposes only:
Semerci Şahin, R., et al. (2026). The effect of cold therapy on vincristine-induced peripheral neuropathy in pediatric oncology patients: A pilot randomized controlled trial. European Journal of Oncology Nursing, 84, 103319.
Additionally, the findings were presented at the 58th Congress of the International Society of Paediatric Oncology (SIOP 2026) in San Antonio, USA, where the study received the SIOP Top Research Award.