Abstract

Introduction: Medication administration errors (MAEs) remain a persistent threat to patient safety, particularly in outpatient infusion settings where biologic therapies are complex and administered via multiple routes. Inconsistent medication administration practices and limited structured feedback mechanisms contribute to preventable errors.

Purpose: This quality improvement project evaluated the impact of the Medication Administration Evaluation and Feedback Tool (MAEFT) on clinician adherence to the “Rights” of safe medication administration and its effectiveness in reducing reported MAEs in outpatient infusion clinics.

Methods: A pre–post observational design was conducted across four outpatient infusion clinics. Data was collected using three complementary sources of the MAEFT: direct observation checklist, clinician self-evaluation surveys using the MAEFT Likert scale, and organizational incident reports. Statistical analyses included descriptive statistics, the chi-square test, and Fisher's exact test.

Results: Overall adherence to medication administration rights improved from 81.0% pre-implementation to 97.0% post-implementation. These improvements were associated with a 73% reduction in reported MAEs. Route-specific analysis demonstrated statistically significant improvements across multiple administration types, with intravenous medication administration showing the greatest improvement, increasing from a mean of 78.1% (SD = 9.87) pre-implementation to 97.1% (SD = 5.03) post-implementation. Clinician self-evaluations (n = 9 nurses) reflected increased perceived competence and adherence following MAEFT implementation.

Conclusion: Implementation of the MAEFT significantly improved medication administration adherence and reduced reported MAEs in outpatient infusion settings. Integrating structured evaluation and feedback tools into routine workflow and competency assessment may support sustained improvements in medication administration safety in outpatient infusion clinics.

Description

This paper was completed as part of a Doctor of Nursing Practice (DNP) clinical course focused on quality improvement and systems leadership. The assignment required the design, implementation, and evaluation of a Quality Improvement Project (QIP) addressing a clinical practice problem. The project evaluated adherence to safe medication administration practices in outpatient biologic infusion clinics using a structured observation and feedback tool, with an emphasis on improving patient safety and reducing medication administration errors.

Author Details

Valerie M. Brady, DNP(c), MSN-Ed, APRN, FNP-C

Credentials: Advanced Practice Registered Nurse (APRN); Family Nurse Practitioner-Certified (FNP-C); Registered Nurse (RN); Doctor of Nursing Practice Candidate

Years of Nursing Experience: 25+ years Areas of Expertise: Medication safety and error reduction, outpatient infusion therapy, quality improvement and program evaluation, clinical education and nursing faculty instruction, simulation-based learning, maternal-child and pediatric nursing, telehealth and virtual care delivery, healthcare workforce education, and care of underserved and vulnerable populations.

Author Bio: Valerie Brady is a Doctor of Nursing Practice (DNP) candidate and board-certified Family Nurse Practitioner with over 25 years of diverse nursing experience spanning clinical practice, leadership, and academic instruction. She holds a Master of Science in Nursing Education and has served as a faculty member at Arizona State University’s Edson College of Nursing and Health Innovation since 2013, contributing extensively to didactic teaching, simulation-based education, and curriculum development.

Her advanced practice experience includes outpatient infusion therapy, telehealth, pediatric specialty care, and clinical operations management across multi-state healthcare systems. She has led large-scale clinical education initiatives, overseeing training and competency development for more than 200 healthcare staff across 40+ clinics.

Dr. Brady’s scholarly work focuses on medication safety, quality improvement in high-risk outpatient settings, and the implementation of evidence-based interventions to reduce medication administration errors. Her work emphasizes system-level change, clinician adherence to safety practices, and improving patient outcomes through structured evaluation and feedback mechanisms. She is also committed to advancing health equity and improving access to care for underserved populations.

Faculty Advisor Details: Misty L. Pagán, DNP, MSN, APRN, AGNP-C

Sigma Membership

Beta Upsilon

Type

DNP Capstone Project

Format Type

Text-based Document

Study Design/Type

Quality Improvement

Research Approach

Quantitative Research

Keywords:

Drug Administration, Medication Errors, Infusions, Outpatient, Outpatient Medical Care

Advisor

Misty L. Pagan

Degree

DNP

Degree Grantor

Northern Arizona University

Degree Year

2026

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record. All permission requests should be directed accordingly and not to the Sigma Repository. All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.

Review Type

None: Degree-based Submission

Acquisition

Self-submission

Date of Issue

2026-05-15

Full Text of Presentation

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Available for download on Monday, November 15, 2027

Click on the above link to access the paper.

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