Abstract

This assessor-blinded, multicenter randomized controlled trial aimed to examine the effectiveness of a peer-facilitated, recovery-focused self-management of Psychosis (PRSP) program supported by a psychiatric nurse (case manager) in improving recovery, mental state, problem-solving ability and other health outcomes of adults with early-stage psychosis over an 18-month follow-up (at immediately and 9 and 18 months post-intervention). The effects of the PRSP were compared with a nurse-led psychoeducation and a usual care group.

198 Chinese patients with early-stage psychosis randomly selected from 4 Community Centers for Mental Wellness (Feb-Aug 2023) and randomly assigned into 1 of the 3 study groups (PRSP, psychoeducation or usual care group) by matching with computerized random numbers. After 4-month interventions, the outcome mean scores were measured at the three post-tests and analyzed on an intention-to-treat basis using Generalised Estimating Equation test.

There were not any adverse events or harms reported/found in the study period. Significant interaction (Grp×Time) treatment effects of the PRSP were found on five outcomes (recovery, psychotic symptoms, functioning, problem-solving, and service satisfaction) between three groups over the 18-month follow-ups, Wald χ2=8.45–22.01, p=0.02-0.001, with moderate to large effect sizes (η2=0.12-0.29). Pairwise contrasts tests indicated that compared to usual care, the PRSP reported significantly greater improvements in recovery, psychotic symptoms, functioning, and service satisfaction at the 3 post-tests (p=0.01-0.005; large effects, Cohen’s d=0.8-1.2). Levels of recovery, problem-solving, and functioning of the PRSP were significantly greater improved than the psychoeducation group at the 3rd post-test (18-month) with moderate effect sizes (Cohen’s d=0.6-0.8). Intervention completion (89.4% attended ≥7 sessions), attendance (average 90.1%) and attrition (9.0%) rates in the PRSP were better than the psychoeducation group (84.8%; average 83.3%; 12.1%, accordingly).

The findings provide evidence about the sustainable effects (18 months) of the peer-facilitated illness self-management program supported by a psychiatric nurse on improving psychotic patients’ recovery, functioning, and service satisfaction. Self-management of psychosis through effective problem-solving strategies, together with nurse and co-patient supports, can be useful in early intervention service in views of inadequate healthcare resources.

Notes

References:

Chien, W.T., Chong, Y.Y., Bressington, D., & McMaster, C.W. (2024). A randomized controlled trial of an acceptance-based, insight-inducing medication adherence therapy (AIM-AT) for adults with early-stage psychosis. Psychiatry Research, 339, 116046. https://doi.org/10.1016/j.psychres.2024.116046.

Chien, W.T., Clifton, A.V., Zhao, S., and Lui, S., 2019. Peer support for people with schizophrenia or other serious mental illness. Cochrane Database of Systematic Reviews (4), CD010880. http://dx.doi.org/10.1002/14651858.CD010880.pub2.

Johnson, S., Lamb, D., Marston, L., Osborn, D., Mason, O., Henderson, C., Ambler, G., Milton, A., Davidson, M., Christoforou, M., Sullivan, S., Hunter, R., Hindle, D., Paterson, B., Leverton, M., and et al., 2018. Peer-supported self-management for people discharged from a mental health crisis team: A randomised controlled trial. The Lancet 392(10145), 409 - 418. https://doi.org/10.1016/S0140-6736(18)31470-3.

Description

This is an assessor-blinded, multicenter RCT examining the effects of a peer-facilitated, recovery-focused self-management of Psychosis (PRSP) program supported by a psychiatric nurse at immediately and 9 and 18 months post-intervention. When compared with a psychoeducation and a usual-care-only group (n=66/group), based on ITT principle, the PRSP (n=66) reported significantly greater improvements in recovery, psychotic symptoms, functioning, and service satisfaction at the 18-month follow-up.

Author Details

Wai Tong Chien, PhD, BN(Hons), RMN, FAAN, FHKAN; Richard Gray, PhD, MSc, RMN

Sigma Membership

Pi Iota at-Large

Type

Presentation

Format Type

Text-based Document

Study Design/Type

Randomized Controlled Trial

Research Approach

Quantitative Research

Keywords:

Testing Strategies, Long-term Care, Implementation Science, Psychosis, Early-stage Psychosis

Conference Name

36th International Nursing Research Congress

Conference Host

Sigma Theta Tau International

Conference Location

Seattle, Washington, USA

Conference Year

2025

Rights Holder

All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record.

Review Type

Abstract Review Only: Reviewed by Event Host

Acquisition

Proxy-submission

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Effects of a Peer-Facilitated, Recovery-Focused Illness Self-Care Program for Early-Stage Psychosis

Seattle, Washington, USA

This assessor-blinded, multicenter randomized controlled trial aimed to examine the effectiveness of a peer-facilitated, recovery-focused self-management of Psychosis (PRSP) program supported by a psychiatric nurse (case manager) in improving recovery, mental state, problem-solving ability and other health outcomes of adults with early-stage psychosis over an 18-month follow-up (at immediately and 9 and 18 months post-intervention). The effects of the PRSP were compared with a nurse-led psychoeducation and a usual care group.

198 Chinese patients with early-stage psychosis randomly selected from 4 Community Centers for Mental Wellness (Feb-Aug 2023) and randomly assigned into 1 of the 3 study groups (PRSP, psychoeducation or usual care group) by matching with computerized random numbers. After 4-month interventions, the outcome mean scores were measured at the three post-tests and analyzed on an intention-to-treat basis using Generalised Estimating Equation test.

There were not any adverse events or harms reported/found in the study period. Significant interaction (Grp×Time) treatment effects of the PRSP were found on five outcomes (recovery, psychotic symptoms, functioning, problem-solving, and service satisfaction) between three groups over the 18-month follow-ups, Wald χ2=8.45–22.01, p=0.02-0.001, with moderate to large effect sizes (η2=0.12-0.29). Pairwise contrasts tests indicated that compared to usual care, the PRSP reported significantly greater improvements in recovery, psychotic symptoms, functioning, and service satisfaction at the 3 post-tests (p=0.01-0.005; large effects, Cohen’s d=0.8-1.2). Levels of recovery, problem-solving, and functioning of the PRSP were significantly greater improved than the psychoeducation group at the 3rd post-test (18-month) with moderate effect sizes (Cohen’s d=0.6-0.8). Intervention completion (89.4% attended ≥7 sessions), attendance (average 90.1%) and attrition (9.0%) rates in the PRSP were better than the psychoeducation group (84.8%; average 83.3%; 12.1%, accordingly).

The findings provide evidence about the sustainable effects (18 months) of the peer-facilitated illness self-management program supported by a psychiatric nurse on improving psychotic patients’ recovery, functioning, and service satisfaction. Self-management of psychosis through effective problem-solving strategies, together with nurse and co-patient supports, can be useful in early intervention service in views of inadequate healthcare resources.