Other Titles
Enhancing Clinical Trial Literacy in Singapore: A DNP Evaluation of a Health Belief Model-Guided Educational Video [Poster Title]
Abstract
Background: Clinical trials are a cornerstone of modern healthcare [4]. However, approximately 80% of trials fail to enrol participants on time, costing millions and delaying essential treatment [1].This directly impedes progress toward Sustainable Development Goal Target 3.b. In Singapore, community participation remains modest due to micro-level barriers, including misconceptions, fear of exploitation, and limited research literacy. Advanced nursing leadership must promote this by promoting research literacy and informed ethical decision-making.
Purpose: The purpose is to systematically evaluate the effectiveness and implementation feasibility of a short, culturally-tailored educational video designed to enhance public knowledge, perceived safety, and willingness to participate in clinical trials among adults in Singapore.
Theoretical Framework: The project is dually grounded in implementation and behavioural science. The HBM guides the content design to target core psychosocial determinants (Perceived Barriers, Benefits, Self-Efficacy). The RE-AIM framework guides the evaluation to ensure translational rigor across five domains: Reach, Effectiveness, Adoption, Implementation, and Maintenance [2].
Methods: A single-group, quasi-experimental pre-post-test (T0-T1) design will be used. Recruitment targets is approximately 200 anonymous participants via a dual-stream convenience sample (social media/IM and clinical posters). The intervention involves a 15-minute online session: Implied Consent - T0 Survey (HBM/Demographics) - Educational Video - T1 Survey (HBM/RE-AIM). Effectiveness is determined by comparing the mean change in HBM scores (T1- T0) using Paired Samples t-tests. Implementation will be assessed using video completion rates, usability metrics, and qualitative thematic analysis of open-text feedback.
Implications for Nursing: This project establishes evidence for integrating a theory-driven digital intervention as an ethical standard of care, ensuring informed consent is truly understood [3]. It exemplifies the DNP role to spearhead systemic transformation, using digital health innovation to bridge the gap between clinical science and the community. Findings will inform policy at the clinical (Adoption) and national level, strengthening the nursing profession’s role as leaders in health literacy and research ethics, and directly supporting the national efforts to meet global health targets (SDG 3).
Notes
References:
1. Brøgger-Mikkelsen, M., Ali, Z., Zibert, J. R., Andersen, A. D., & Thomsen, S. F. (2020). Online Patient Recruitment in Clinical Trials: Systematic Review and Meta-Analysis. J Med Internet Res, 22(11), e22179. https://doi.org/10.2196/22179
2. Glasgow, R. E., Harden, S. M., Gaglio, B., Rabin, B., Smith, M. L., Porter, G. C., Ory, M. G., & Estabrooks, P. A. (2019). RE-AIM planning and evaluation framework: adapting to new science and practice with a 20-year review. Frontiers in public health, 7, 64.
3. Cowdery, J. E., Powell, J. H., Fleming, Y. A., & Brown, D. L. (2019). Effectiveness of a short video-based educational intervention on factors related to clinical trial participation in adolescents and young adults: a pre-test/post-test design. Trials, 20(1), 7. https://doi.org/10.1186/s13063-018-3097-2
4.Zhang, H., & Jiang, X. (2025). Importance of clinical trials and contributions to contemporary medicine: commentary. Ann Med, 57(1), 2451190. https://doi.org/10.1080/07853890.2025.2451190
Sigma Membership
Non-member
Type
Poster
Format Type
Text-based Document
Study Design/Type
Quasi-Experimental Study, Other
Research Approach
Quantitative Research
Keywords:
Theory, Public and Community Health, Sustainable Development Goals, Nursing Research, Information Literacy, Nurse Practitioners, Health Belief Model, Singapore
Recommended Citation
Velu, Harini S. Shunmuga; Young, Barnaby Edward; and Zhou, Wentao, "Enhancing Clinical Trial Literacy in Singapore: A DNP Evaluation of a HBM-Guided Educational Video" (2026). International Nursing Research Congress (INRC). 100.
https://www.sigmarepository.org/inrc/2026/posters_2026/100
Conference Name
37th International Nursing Research Congress
Conference Host
Sigma Theta Tau International
Conference Location
Toronto, Ontario, Canada
Conference Year
2026
Rights Holder
All rights reserved by the author(s) and/or publisher(s) listed in this item record unless relinquished in whole or part by a rights notation or a Creative Commons License present in this item record. All permission requests should be directed accordingly and not to the Sigma Repository. All submitting authors or publishers have affirmed that when using material in their work where they do not own copyright, they have obtained permission of the copyright holder prior to submission and the rights holder has been acknowledged as necessary.
Review Type
Abstract Review Only: Reviewed by Event Host
Acquisition
Proxy-submission
Date of Issue
2026-09-06
Enhancing Clinical Trial Literacy in Singapore: A DNP Evaluation of a HBM-Guided Educational Video
Toronto, Ontario, Canada
Background: Clinical trials are a cornerstone of modern healthcare [4]. However, approximately 80% of trials fail to enrol participants on time, costing millions and delaying essential treatment [1].This directly impedes progress toward Sustainable Development Goal Target 3.b. In Singapore, community participation remains modest due to micro-level barriers, including misconceptions, fear of exploitation, and limited research literacy. Advanced nursing leadership must promote this by promoting research literacy and informed ethical decision-making.
Purpose: The purpose is to systematically evaluate the effectiveness and implementation feasibility of a short, culturally-tailored educational video designed to enhance public knowledge, perceived safety, and willingness to participate in clinical trials among adults in Singapore.
Theoretical Framework: The project is dually grounded in implementation and behavioural science. The HBM guides the content design to target core psychosocial determinants (Perceived Barriers, Benefits, Self-Efficacy). The RE-AIM framework guides the evaluation to ensure translational rigor across five domains: Reach, Effectiveness, Adoption, Implementation, and Maintenance [2].
Methods: A single-group, quasi-experimental pre-post-test (T0-T1) design will be used. Recruitment targets is approximately 200 anonymous participants via a dual-stream convenience sample (social media/IM and clinical posters). The intervention involves a 15-minute online session: Implied Consent - T0 Survey (HBM/Demographics) - Educational Video - T1 Survey (HBM/RE-AIM). Effectiveness is determined by comparing the mean change in HBM scores (T1- T0) using Paired Samples t-tests. Implementation will be assessed using video completion rates, usability metrics, and qualitative thematic analysis of open-text feedback.
Implications for Nursing: This project establishes evidence for integrating a theory-driven digital intervention as an ethical standard of care, ensuring informed consent is truly understood [3]. It exemplifies the DNP role to spearhead systemic transformation, using digital health innovation to bridge the gap between clinical science and the community. Findings will inform policy at the clinical (Adoption) and national level, strengthening the nursing profession’s role as leaders in health literacy and research ethics, and directly supporting the national efforts to meet global health targets (SDG 3).
Description
This project evaluates an HBM-guided video intervention to boost public knowledge and trust in clinical trials in Singapore. Using a pre-post design and RE-AIM, it measures effectiveness against behavioral determinants (knowledge, safety, willingness) and assesses feasibility for institutional adoption. This demonstrates advanced nursing leadership in digital health, creating a sustainable, evidence-based resource to transform ethical public engagement in clinical research and support SDG 3.